Characterization of cellular and humoral immune responses in pemphigus patients and an HLA-transgenic mouse model

Characterization of cellular and humoral immune responses in pemphigus patients and an HLA-transgenic mouse model

The rare, but potentially fatal autoimmune disorder pemphigus is considered as a prototypical antibody-mediated organ-specific disease, in which immunoglobulin (Ig) G autoantibodies (auto-ab) mainly target the desmosomal cadherins Desmoglein 3 (Dsg3) and Dsg1 within the epidermis. This process, refe...

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Bibliografiske detaljer
Hovedforfatter: Hennerici, Tina
Andre forfattere: Eming, Rüdiger (PD Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2016
Fag:
Autoantibodies
Autoimmunität
Antikörper
Autoantikörper
Medizin
Autoimmunity
Medical sciences Medicine
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