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Selective targeting of immunoproteasome subunit LMP7 prevents colitis-associated carcinogenesis
Chronic inflammation is a well-known risk factor for the development of colonic tumorigenesis. In this study, we show that the immunoproteasome (iP) subunit LMP7 plays a crucial role in the progression of colitis-associated carcinogenesis (CAC). The activity and function of the iP complex has been e...
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| 主要作者: | |
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| 其他作者: | |
| 格式: | Dissertation |
| 語言: | 英语 |
| 出版: |
Philipps-Universität Marburg
2016
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| 主題: | |
| 在線閱讀: | PDF-Volltext |
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PDF-Volltext| 索引號: |
urn:nbn:de:hebis:04-z2016-08958 |
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| Publikationsdatum: |
2016-12-14 |
| Datum der Annahme: |
2016-11-14 |
| Downloads: |
35 (2024), 121 (2023), 137 (2022), 111 (2021), 62 (2020), 123 (2019), 25 (2018) |
| Lizenz: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
| Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2016/0895 https://doi.org/10.17192/z2016.0895 |