Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II
Two pathological relevant proteins, human aldose reductase and human carbonic anhydrase, were used as model proteins to get insights into the process of molecular recognition. The thermodynamics and kinetics of the formation process of protein ligand complex formation were studied.
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פורמט: | Dissertation |
שפה: | אנגלית |
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Philipps-Universität Marburg
2015
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גישה מקוונת: | PDF-Volltext |
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סיכום: | Two pathological relevant proteins, human aldose reductase and human carbonic anhydrase, were used as model proteins to get insights into the process of molecular recognition. The thermodynamics and kinetics of the formation process of protein ligand complex formation were studied. |
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תיאור פיזי: | 245 Seiten |
DOI: | 10.17192/z2015.0464 |