Functional analysis of the histone arginine methyltransferase PRMT6

Functional analysis of the histone arginine methyltransferase PRMT6

Aberrant expression of several PRMTs is linked to the pathogenesis of human cancer. PRMTs catalyse the arginine methylation of many substrates, which are implicated in cancer development, progression and aggressiveness. In this context, only few studies investigated PRMT6 so far and its possible rol...

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Autore principale: Riedl, Stefanie
Altri autori: Bauer, Uta-Maria (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2014
Soggetti:
DNA Reparatur
cancer
Medizin
senescence
PRMT6
DNA repair
Seneszenz
proliferation
arginine methyltransferase
Tumorsuppressorgene
Krebs
tumour suppressor genes
Proliferation
Arginin-Methyltransferase
Medical sciences Medicine
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