Regulation of Rho-activating proteins by heterotrimeric G proteins: Sensitivity of Gα RhoGEF interaction is determined by dissociation kinetics

Regulation of Rho-activating proteins by heterotrimeric G proteins: Sensitivity of Gα RhoGEF interaction is determined by dissociation kinetics

Activation of RhoGTPases downstream of G protein coupled receptors is important for many physiological functions, such as blood pressure regulation. The subfamilies Rho, Rac and Cdc42 are the best understood RhoGTPases and the present study focused on signaling towards the Rho subfamily member RhoA....

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Gorde:
Xehetasun bibliografikoak
Egile nagusia: Bodmann, Eva-Lisa
Beste egile batzuk: Bünemann, Moritz (Prof.) (Tesi aholkularia)
Formatua: Dissertation
Hizkuntza:ingelesa
Argitaratua: Philipps-Universität Marburg 2014
Gaiak:
Regulator of G protein signaling 2
Gα13
Biowissenschaften, Biologie
p63RhoGEF
Förster resonance energy transfer
Gαq
Fluoreszenz-Resonanz-Energie-Transfer
leukemia-associated RhoGEF
G-Protein gekoppelte Rezeptoren
Leukämie assoziiertes RhoGEF
Life sciences
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Aleari buruzko argibideak
Sailkapena: urn:nbn:de:hebis:04-z2014-04749
Argitaratze data: 2015-06-25
Datum der Annahme: 2014-11-14
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL sarbidea: https://archiv.ub.uni-marburg.de/diss/z2014/0474
https://doi.org/10.17192/z2014.0474

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