PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia

The acute promyelocytic leukaemia (APL) accounts for 10% of the adult AML patients. APL patients carry chromosomal translocations involving the rarα gene on chromosome 17. The most frequent translocations lead to the expression of the fusion proteins PML/RARα (98%; t(15;17)) and PLZF/RARα (1%; t(11;...

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主要作者: Frech, Miriam
其他作者: Renkawitz-Pohl, Renate (Prof. Dr.) (BetreuerIn (Doktorarbeit))
格式: Dissertation
语言:英语
出版: Philipps-Universität Marburg 2014
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索引号: urn:nbn:de:hebis:04-z2014-00752
Publikationsdatum: 2014-02-19
Datum der Annahme: 2014-01-31
Downloads: 50 (2024), 95 (2023), 38 (2022), 43 (2021), 5 (2020), 23 (2019), 23 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
访问URL: https://archiv.ub.uni-marburg.de/diss/z2014/0075
https://doi.org/10.17192/z2014.0075