PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia

PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia

The acute promyelocytic leukaemia (APL) accounts for 10% of the adult AML patients. APL patients carry chromosomal translocations involving the rarα gene on chromosome 17. The most frequent translocations lead to the expression of the fusion proteins PML/RARα (98%; t(15;17)) and PLZF/RARα (1%; t(11;...

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Autor principal: Frech, Miriam
Altres autors: Renkawitz-Pohl, Renate (Prof. Dr.) (Assessor de tesis)
Format: Dissertation
Idioma:anglès
Publicat: Philipps-Universität Marburg 2014
Matèries:
Translokation
differentiation block
Naturwissenschaften
Chromosomenaberration
Leukämie
acute promyelocytic leukaemia
high molecular weight complex
Akute myeloische Leukämie
Natural sciences & mathematics
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Signatura: urn:nbn:de:hebis:04-z2014-00752
Data de publicació: 2014-02-19
Datum der Annahme: 2014-01-31
Downloads: 49 (2024), 95 (2023), 38 (2022), 43 (2021), 5 (2020), 23 (2019), 23 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL d'accés: https://archiv.ub.uni-marburg.de/diss/z2014/0075
https://doi.org/10.17192/z2014.0075

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