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PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia
The acute promyelocytic leukaemia (APL) accounts for 10% of the adult AML patients. APL patients carry chromosomal translocations involving the rarα gene on chromosome 17. The most frequent translocations lead to the expression of the fusion proteins PML/RARα (98%; t(15;17)) and PLZF/RARα (1%; t(11;...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2014
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| 在线阅读: | PDF-Volltext |
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