PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia
The acute promyelocytic leukaemia (APL) accounts for 10% of the adult AML patients. APL patients carry chromosomal translocations involving the rarα gene on chromosome 17. The most frequent translocations lead to the expression of the fusion proteins PML/RARα (98%; t(15;17)) and PLZF/RARα (1%; t(11;...
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Materyal Türü: | Dissertation |
Dil: | İngilizce |
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Philipps-Universität Marburg
2014
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Online Erişim: | PDF Tam Metin |
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