PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia

PLZF/RARalpha binding partners and their influence on the induction of acute promyelocytic leukaemia

The acute promyelocytic leukaemia (APL) accounts for 10% of the adult AML patients. APL patients carry chromosomal translocations involving the rarα gene on chromosome 17. The most frequent translocations lead to the expression of the fusion proteins PML/RARα (98%; t(15;17)) and PLZF/RARα (1%; t(11;...

Fuld beskrivelse

Gespeichert in:
Bibliografiske detaljer
Hovedforfatter: Frech, Miriam
Andre forfattere: Renkawitz-Pohl, Renate (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2014
Fag:
Translokation
differentiation block
Naturwissenschaften
Chromosomenaberration
Leukämie
acute promyelocytic leukaemia
high molecular weight complex
Akute myeloische Leukämie
Natural sciences & mathematics
Online adgang:PDF-Volltext
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
No citations were found for this record.

Lignende værker