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lin-Benzopurines as Inhibitors of tRNA-Guanine Transglycosylase: Perturbance of Homodimer Formation, Import of Water Clusters and Determinants of Crystallographical Disorder
In this thesis different methods of structure-based drug design have been applied to develop TGT inhibitors suiting the manifold purposes of the tackled projects. TGT is not only a putative target for the treatment of Shigellosis, but additionally represents a well-accessible model system to study m...
保存先:
| 第一著者: | |
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| その他の著者: | |
| フォーマット: | Dissertation |
| 言語: | 英語 |
| 出版事項: |
Philipps-Universität Marburg
2012
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| 主題: | |
| オンライン･アクセス: | PDFフルテキスト |
| タグ: |
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インターネット
PDFフルテキスト| 請求記号: |
urn:nbn:de:hebis:04-z2013-00742 |
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| 出版日付: |
2013-02-11 |
| Datum der Annahme: |
2013-01-30 |
| Downloads: |
46 (2024), 127 (2023), 114 (2022), 89 (2021), 120 (2020), 85 (2019), 62 (2018) |
| Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
| アクセスURL: |
https://archiv.ub.uni-marburg.de/diss/z2013/0074 https://doi.org/10.17192/z2013.0074 |