Analysis of the Host Stress Response to Ebola Virus Infection and Generation of a Recombinant Marburg Virus Expressing EGFP to Study Viral Spread

Analysis of the Host Stress Response to Ebola Virus Infection and Generation of a Recombinant Marburg Virus Expressing EGFP to Study Viral Spread

Ebola virus (EBOV) and Marburg virus (MARV) belong to the filovirus family and cause outbreaks with case fatality rates up to 90%. Currently there is no approved vaccine or antiviral treatment available. Therefore filoviruses are classified as priority A select agents, which can only be handled in h...

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Dettagli Bibliografici
Autore principale: Schmidt, Kristina Maria
Altri autori: Renkawitz-Pohl, Renate (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2012
Soggetti:
Marburg-Virus-Krankheit
Processing body
Stressreaktion
VP35
Ebola virus, Recombinant Marburg virus expressing EGFP
Ebola-Virus
PACT
Stress granule
VP30
Fluoreszenz
Biowissenschaften, Biologie
NP
Protein-Serin-Threonin-Kinasen
PKR
Life sciences
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