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Nef from SIVmac239 down-modulates cell surface CXCR4 in tumor cells and inhibits proliferation, migration and angiogenesis
Aim: To evaluate if the lentiviral accessory protein Nef can down-regulate CXCR4 in tumor cells and affect tumor cell proliferation, migration and angiogenesis. Materials and Methods: HeLa-ACC cells were transfected with Nef from SIVmac239 and expression levels of cell surface CXCR4 were monitored b...
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| 格式: | Dissertation |
| 语言: | 英语 |
| 出版: |
Philipps-Universität Marburg
2012
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| 主题: | |
| 在线阅读: | PDF-Volltext |
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PDF-Volltext| 索引号: |
urn:nbn:de:hebis:04-z2011-08778 |
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| Publikationsdatum: |
2012-02-09 |
| Datum der Annahme: |
2012-01-06 |
| Downloads: |
24 (2024), 71 (2023), 112 (2022), 85 (2021), 62 (2020), 92 (2019), 47 (2018) |
| Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
| 访问URL: |
https://archiv.ub.uni-marburg.de/diss/z2011/0877 https://doi.org/10.17192/z2011.0877 |