Nef from SIVmac239 down-modulates cell surface CXCR4 in tumor cells and inhibits proliferation, migration and angiogenesis
Aim: To evaluate if the lentiviral accessory protein Nef can down-regulate CXCR4 in tumor cells and affect tumor cell proliferation, migration and angiogenesis. Materials and Methods: HeLa-ACC cells were transfected with Nef from SIVmac239 and expression levels of cell surface CXCR4 were monitored b...
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格式: | Dissertation |
語言: | 英语 |
出版: |
Philipps-Universität Marburg
2012
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在線閱讀: | PDF-Volltext |
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PDF-Volltext索引號: |
urn:nbn:de:hebis:04-z2011-08778 |
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Publikationsdatum: |
2012-02-09 |
Datum der Annahme: |
2012-01-06 |
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https://rightsstatements.org/vocab/InC-NC/1.0/ |
Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2011/0877 https://doi.org/10.17192/z2011.0877 |