Synthesis and Analytics of Rigidified Peptide Architectures: Neuropeptide Y Dipeptide Scan, Ring-Chain-Equilibria of Iminopeptides, Thiazole Amino Acids for Thiopeptide Antibiotics

Synthesis and Analytics of Rigidified Peptide Architectures: Neuropeptide Y Dipeptide Scan, Ring-Chain-Equilibria of Iminopeptides, Thiazole Amino Acids for Thiopeptide Antibiotics

The architectures (three-dimensional shapes) of peptides determine their respective biological functions. Therefore, the correct alignment of functionalities in a structure by constraining the flexibility is a key process in evolution as well as in medicinal chemistry in order to increase binding af...

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Bibliographic Details
Main Author: Enck, Sebastian
Contributors: Geyer, Armin (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2010
Subjects:
Organic synthesis
NMR-Spektroskopie
Vororientierung
Peptide antibiotics
Organische Synthese
Thiazoles
Entropiebilanz
Scanning
Macrocyclisierung
Thiazole
Macrocyclization
NMR spectroscopy
Chemie
Peptidantibiotikum
Chemistry & allied sciences
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Call Number: urn:nbn:de:hebis:04-z2010-05644
Publication Date: 2010-10-13
Date of Acceptance: 2010-08-13
Downloads: 98 (2024), 141 (2023), 59 (2022), 99 (2021), 97 (2020), 92 (2019), 38 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2010/0564
https://doi.org/10.17192/z2010.0564

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