Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

In this thesis, toxicity of PEI-based non-viral vector systems for siRNA application into the lungs was comprehensively described and analyzed in vitro as well as in vivo. Chapter 1 introduced in basic information about the lung anatomy and physiology and general considerations for pulmonary appli...

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主要作者: Beyerle, Andrea
其他作者: Kissel, Thomas (Prof.) (BetreuerIn (Doktorarbeit))
格式: Dissertation
語言:英语
出版: Philipps-Universität Marburg 2010
主題:
inflammation
Polyethylenimin (PEI)
pulmonary application
RNS-Interferenz
siRNA
Toxikologische Bewertung
Naturwissenschaften
Cytotoxicity
Wasserlösliche Polymere
Oxidativer Stress
Entzündung
In vivo
Lunge
Cytotoxizität
In vitro
Poly(ethylene imine)
oxidative stress
Natural sciences & mathematics
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持有資料詳情
索引號: urn:nbn:de:hebis:04-z2010-01360
Publikationsdatum: 2010-05-10
Datum der Annahme: 2010-04-14
Downloads: 33 (2024), 81 (2023), 178 (2022), 275 (2021), 207 (2020), 440 (2019), 250 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2010/0136
https://doi.org/10.17192/z2010.0136

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