Investigation of the functions of 53BP1 in DNA demethylation
DNA damage can be caused by various forms of genotoxic stress, including endogenous (reactive oxygen species, abnormal replication intermediates) and exogenous (UV, IR, and reactive chemicals) sources. DNA double-strand break (DSB) is believed to be one of the most serious lesions to cells becaus...
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Format: | Dissertation |
Sprog: | engelsk |
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Philipps-Universität Marburg
2009
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