TGT a Drug Target to Study pKa Shifts, Residual Solvation & Protein-Protein Interface Formation
In this thesis multiple computer aided methods of structure based drug design along with X-ray crystallography and kinetic measurements were used to investigate inhibitors of tRNA-guanine transglycosylase (TGT) a putative target for a new specific antibiotic against Shigella bacteria. Within a year...
Bewaard in:
Hoofdauteur: | |
---|---|
Andere auteurs: | |
Formaat: | Dissertation |
Taal: | Engels |
Gepubliceerd in: |
Philipps-Universität Marburg
2009
|
Onderwerpen: | |
Online toegang: | PDF Full text |
Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|
No references were found for this record.