Non-Viral Delivery of Nucleic Acids and Image-Guided Assessment of in vivo Performance of Multifunctional Nanomedicines

Non-Viral Delivery of Nucleic Acids and Image-Guided Assessment of in vivo Performance of Multifunctional Nanomedicines

In this thesis, new and multifunctional non-viral vectors for delivery of nucleic acids were synthesized and characterized concerning biophysicochemical parameters. Chapter 1 introduces into the field of nanomedicine which advanced drug delivery systems can be numbered among. Chapter 2 describes t...

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Bibliografiska uppgifter
Huvudupphovsman: Merkel, Olivia Monika
Övriga upphovsmän: Kissel, Thomas (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:engelska
Publicerad: Philipps-Universität Marburg 2009
Ämnen:
Gene Knockdown Techniques
Radionuklid
Polyethylenimin
Tierm
Gamma Camera Imaging
Gene Delivery
Pharmakokinetik
Polymere
Polyethyleneimine
Nanotechnologie
RNS-Interferenz
Biodistribution
Gentherapie
Naturwissenschaften
SPECT
Pharmacokinetics
Polyethyleniminderivate
Small Interfering RNA
Natural sciences & mathematics
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