Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Muconyl-CoA, 2-hydroxyadipoyl-CoA, oxalocrotonyl-CoA and butynedioyl- CoA were synthesised and characterised as substrates of the (R)-2- hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. The specificity of the enzyme for these substrates were determined and the reaction products identi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Parthasarathy, Anutthaman
Awduron Eraill: Buckel, Wolfgang (Prof. Dr.) (Cynghorydd traethodau ymchwil)
Fformat: Dissertation
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2009
Pynciau:
Hydroxyglutaryl-CoA-Dehydratase <2->
Clostridium propionicum
[4Fe-4S] Cluster
Biowissenschaften, Biologie
Coenzym A
Lactyl-CoA, Dehydration
Acidaminococcus fermentans
[4Fe-4S] cluster
Clostridium symbiosum
2-Hydroxyglutarat-Dehydrogenase
2-hydroxyglutaryl-CoA, lactyl-CoA
Dehydratase
Life sciences
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