Pharmakogenetik der Wachstumshormonsubstitution bei Hypophysenvorderlappeninsuffizienz: Der Collagen-I-alpha-1-SP1-Polymorphismus

Es besteht ein COLIa1-SP1-Polymorphismus assoziierter Effekt auf die individuell subkutan applizierte benötigte hGH-Dosis bei GH-defizienten adulten Patienten. TT-homozygote Polymorphismus-Genotypen (5%) benötigen eine signisfikant niedrigere hGH-Dosis als die GG-homozygoten Genotypen (GG 65%, GT 3...

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Bibliographic Details
Main Author: Horn, Marlitt
Contributors: Kann, P.H. (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2008
Innere Medizin
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Call Number: urn:nbn:de:hebis:04-z2008-09831
Downloads: 51 (2021), 83 (2020), 119 (2019), 50 (2018), 55 (2017)
Source: Pharmacogenomics. 2008 Aug; 9(8): 1017-26
Publication Date: 2009-01-12
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author.
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