The role of the RNA-binding protein Hfq in the model pathogen Salmonella Typhimurium

Hfq is a RNA-binding protein which exists in homohexamers in vivo. Based on its folding, containing the highly conserved Sm1 and Sm2 motifs, it belongs to the growing family of Sm and Sm-like (Lsm) proteins. It has been shown, that Hfq is a pleiotropic regulator in bacteria which is involved in a br...

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Bibliographic Details
Main Author: Sittka, Alexandra
Contributors: Hartmann, Roland (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2008
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Online Access:PDF Full Text
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