One-stage full-mouth disinfection versus subgingivales Scaling an einem Tag oder subgingivales Scaling quadrantenweise bei Patienten mit generalisierter chronischer Parodontitis

Ziel: Das Ziel dieser Langzeitstudie ist es, die Hypothese zu prüfen, ob bei Patienten mit generalisierter chronischer Parodontitis die „one-stage full-mouth disinfection“ zu größeren klinischen und mikrobiologischen Verbesserungen führt als ein subgingivales Scaling an einem Tag oder quadrantenw...

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Tác giả chính: Swierkot, Katrin
Tác giả khác: Mengel, R. (Prof. Dr.) (Cố vấn luận án)
Định dạng: Dissertation
Ngôn ngữ:German
Được phát hành: Philipps-Universität Marburg 2008
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Objective: The aim of this study was to test the hypothesis that the one-stage full-mouth disinfection (FMD) provides greater clinical and microbiological improvement compared to full-mouth scaling and root planing (FM-SRP) within 24 hours and quadrant scaling and root planing (Q-SRP) in patients with generalized chronic periodontitis. Method: 28 patients were randomised into three groups. The Q-SRP group was scaled quadrantwise at one-week intervals. The two other groups received a one-stage full-mouth scaling with (FMD) and without (FM-SRP) the adjunctive use of chlorhexidine. At baseline, after 1, 2, 4 and 8 months clinical parameters were recorded and microbiological analysis was performed using real-time PCR. Results: All three treatment modalities resulted in significant clinical improvement at any time whereas the medium pockets (4 - 6 mm) of singlerooted teeth showed significant better results than multi-rooted-teeth in all groups. There were only group differences up to after 2 months: in the FM-SRP group was a significantly higher reduction of probing depth and bleeding on probing compared to the other two groups. There were significant reductions of the total bacteria after a period of 8 months with the Q-SRP and FMD treatment. The number of Porphyromonas gingivalis could be significantly reduced in every group, and Aggregatibacter actinomycetemcomitans only in the Q-SRP and FMSRP group. Conclusion: All three treatment modalities lead to an improvement of the clinical and microbiological parameters, however, without significant group differences after 8 months.