Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

The protozoan disease malaria is one of the major inexorable infections worldwide, especially widespread throughout tropical regions. It is caused by parasites of the genus Plasmodium (P. falciparum, P. vivax, P. malariae and P. ovale) and transmitted by female Anopheles mosquitoes. The WHO estimate...

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Bibliografiska uppgifter
Huvudupphovsman: Luksch, Torsten
Övriga upphovsmän: Klebe, Gerhard (Prof.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:engelska
Publicerad: Philipps-Universität Marburg 2008
Ämnen:
Docking
Plasmepsin
Wirkstoffdesign
Malaria
Medizin
MD Simulation
Drug Design
Molecular Dynamics
Medical sciences Medicine
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