Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

The protozoan disease malaria is one of the major inexorable infections worldwide, especially widespread throughout tropical regions. It is caused by parasites of the genus Plasmodium (P. falciparum, P. vivax, P. malariae and P. ovale) and transmitted by female Anopheles mosquitoes. The WHO estimate...

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Bibliografische gegevens
Hoofdauteur: Luksch, Torsten
Andere auteurs: Klebe, Gerhard (Prof.) (Thesis begeleider)
Formaat: Dissertation
Taal:Engels
Gepubliceerd in: Philipps-Universität Marburg 2008
Onderwerpen:
Docking
Plasmepsin
Wirkstoffdesign
Malaria
Medizin
MD Simulation
Drug Design
Molecular Dynamics
Medical sciences Medicine
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