Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

The protozoan disease malaria is one of the major inexorable infections worldwide, especially widespread throughout tropical regions. It is caused by parasites of the genus Plasmodium (P. falciparum, P. vivax, P. malariae and P. ovale) and transmitted by female Anopheles mosquitoes. The WHO estimate...

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Bibliographic Details
Main Author: Luksch, Torsten
Contributors: Klebe, Gerhard (Prof.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2008
Subjects:
Docking
Plasmepsin
Wirkstoffdesign
Malaria
Medizin
MD Simulation
Drug Design
Molecular Dynamics
Medical sciences Medicine
Online Access:PDF Full Text
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