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Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

Yellow fever virus (YFV) is a mosquito-transmitted, enveloped, positive stranded RNA virus belonging to the genus flavivirus, which causes hemorrhagic fever in humans in Africa and South America. The YFV is responsible for 200 000 clinical infections per year including 40 000 deaths. Despite the pre...

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Main Author: Daffis, Stephane
Contributors: ter Meulen, Jan (Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2006
Subjects:
Gelbfieber
Neutralizing epitopes
Antibody fragments
Flaviviren
Gelbfiebervirus
Phagen-Display-Bibliothek
Impfstoff
Virologie
Phage display
Medizin
Yellow fever virus
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-z2006-03881
Publication Date: 2006-06-12
Date of Acceptance: 2006-05-17
Source: Virology
Downloads: 90 (2025), 146 (2024), 72 (2023), 72 (2022), 89 (2021), 114 (2020), 100 (2019), 73 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2006/0388
https://doi.org/10.17192/z2006.0388

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