Identification and functional characterization of protein domains in the transcription factor TWIST

Identification and functional characterization of protein domains in the transcription factor TWIST

Saethre-Chotzen syndrome is an autosomal dominant inherited disorder with premature fusion of cranial sutures. It is caused by nucleotide sequence changes within or in proximity of the TWIST1 gene. This gene encodes for a bHLH transcription factor, which inhibits osteogenic differentiation by transc...

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Autore principale: Singh, Shalini
Altri autori: Kunz, Jürgen (Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2006
Soggetti:
Transcription factor
TWIST
Medizin
Protein domains
Nucleus localization signal
Medical sciences Medicine
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