Identification and functional characterization of protein domains in the transcription factor TWIST

Identification and functional characterization of protein domains in the transcription factor TWIST

Saethre-Chotzen syndrome is an autosomal dominant inherited disorder with premature fusion of cranial sutures. It is caused by nucleotide sequence changes within or in proximity of the TWIST1 gene. This gene encodes for a bHLH transcription factor, which inhibits osteogenic differentiation by transc...

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Bibliografiske detaljer
Hovedforfatter: Singh, Shalini
Andre forfattere: Kunz, Jürgen (Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2006
Fag:
Transcription factor
TWIST
Medizin
Protein domains
Nucleus localization signal
Medical sciences Medicine
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