Zebrafish Trap230/Med12 is required for Sox9 activity and limb induction

Zebrafish Trap230/Med12 is required for Sox9 activity and limb induction

This thesis deals with the mapping and cloning of trapped (tpd), a novel zebrafish mutant found to disrupt an ortholog of Trap230, a member of the Mediator complex. Mediator is a coactivator complex transducing the interaction of DNA-binding transcription factors with RNA polymerase II. The vert...

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Bibliographic Details
Main Author: Rau, Marlene Juliane
Contributors: Renkawitz-Pohl, Renate (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2005
Subjects:
Neural crest
Transkriptionsfaktor
Biowissenschaften, Biologie
Ohren
Brustflossen
Gliedmaßen
Limb development
Otholiten
Netzhaut ,
Sox9
Mediator complex
Transkription
Zebrabärbling
Entwicklungsbiologie
Mediator-Komplex
Transkription <Genetik>
Zebrafish
Melanocyten
Neuralleiste
Life sciences
Online Access:PDF Full Text
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