Insulin nanocomplexes formed by self-assembly from amine-modified poly(vinyl alcohol)-graft-poly(L-Lactide) for non-invasive mucosal delivery: Preparation, characterization and in vivo investigations

Simon, Michael

Insulin nanocomplexes formed by self-assembly from amine-modified poly(vinyl alcohol)-graft-poly(L-Lactide) for non-invasive mucosal delivery: Preparation, characterization and in vivo investigations

In this work biodegradable DEAPA-PVAL-g-PLLA nanocomplexes were investigated as a colloidal peptide carrier system for non-invasive transmucosal insulin delivery. Chapter 1 describes the basic fundamentals of insulin therapy, current status, problems and future trends. The pathogenesis of diabetes m...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Simon, Michael
Άλλοι συγγραφείς:	Kissel, Thomas (Prof. Dr.) (Εισηγητής διατριβής)
Μορφή:	Dissertation
Γλώσσα:	Αγγλικά
Έκδοση:	Philipps-Universität Marburg 2005
Θέματα:	Nanopartikel Drug Delivery System Nasale Applikation Modifizierte Polymere Nichtinvasive Insulinapplikation Therapeutisches System Insulin Non-invasive Application Diabetes mellitus Nanoparticles Modified Polymers Medizin Medical sciences Medicine
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Insulin nanocomplexes formed by self-assembly from amine-modified poly(vinyl alcohol)-graft-poly(L-Lactide) for non-invasive mucosal delivery: Preparation, characterization and in vivo investigations

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