Transcription factor Sp2: Molecular characterization and generation of Sp2 gene targeted mice

Transcription factor Sp2: Molecular characterization and generation of Sp2 gene targeted mice

Summary The Sp family of transcription factors is characterised by its DNA-binding domain, an array of three conserved C2H2 zinc fingers. As a consequence of the conserved DNA binding motif, Sp members recognize GC (GGGGCGGGG) and GT (GGTGTGGGG) boxes with similar specificity and affinity. GC and...

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Bibliographic Details
Main Author: Baur, Frank
Contributors: Renkawitz-Pohl, Renate (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2005
Subjects:
Transkriptionsfaktor
Zinkfinger
Transkription <Genetik>
Biowissenschaften, Biologie
DNS-Bindung
Zinc finger
Knockout <Molekulargenetik>
Life sciences
Online Access:PDF Full Text
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