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Chitosan copolymers for intranasal delivery of insulin: synthesis, characterization and biological properties
Recently, chitosan has been extensively investigated as a promising carrier in the field of drug delivery. To overcome its poor solubility at physiological pH and the cytotoxicity of trimethyl chitosan, PEGylated trimethyl chitosan copolymers were synthesized and characterized systemically for the f...
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| Format: | Doctoral Thesis |
| Language: | English |
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Philipps-Universität Marburg
2004
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| Online Access: | PDF Full Text |
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