Mitogenic signaling by Gq/11-coupled receptors
By binding to their cognate GPCRs, many potent mitogens such as neuropeptides, angiotensin II or lysophosphatidic acid stimulate cell proliferation via engaging the ERK/MAPK cascade. As mentioned before, agonists stimulating Gq/11-coupled receptors activate PLCb isoforms thereby...
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Format: | Doctoral Thesis |
Language: | English |
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Philipps-Universität Marburg
2004
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Online Access: | PDF Full Text |
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