Mitogenic signaling by Gq/11-coupled receptors

Mitogenic signaling by Gq/11-coupled receptors

By binding to their cognate GPCRs, many potent mitogens such as neuropeptides, angiotensin II or lysophosphatidic acid stimulate cell proliferation via engaging the ERK/MAPK cascade. As mentioned before, agonists stimulating Gq/11-coupled receptors activate PLCb isoforms thereby...

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Detalhes bibliográficos
Autor principal: Roelle, Susanne
Outros Autores: Carell, Thomas, Prof. Dr. (Orientador)
Formato: Dissertation
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2004
Assuntos:
mitogenic signaling , phospholipase C
cell proliferation
Neuropeptide
Zellproliferation
Chemie
neuropeptides
Mitogene Signalwege
Phospholipase C
Chemistry & allied sciences
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