Drug Delivery of Oligonucleotides at the Blood-Brain Barrier: a Therapeutic Strategy for Inflammatory Diseases of the Central Nervous System

In this project a vector for drug delivery into brain endothelial cells, consisting of an anti-transferrin receptor antibody and a complex of polyethylenimine (PEI) and an oligodeoxynucleotide (ODN) drug was evaluated. NF-kB decoys are short double-stranded ODNs, which contain a recognition sequence...

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Bibliographic Details
Main Author: Osburg, Berit
Contributors: Voigt, Karlheinz Prof. Dr. med. (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2003
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Call Number: urn:nbn:de:hebis:04-z2003-05516
Downloads: 70 (2021), 50 (2020), 189 (2019), 59 (2018), 61 (2017)
Publication Date: 2003-09-24
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2003/0551
https://doi.org/10.17192/z2003.0551