Quality-controlled characterization of a monoclonal antibody specific to an EC5-domain of human desmoglein 3 for pemphigus research

Background: Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering disease caused mainly by IgG autoantibodies (auto-abs) against the cadherintype adhesion molecules desmoglein (Dsg) 1 and 3. Pathogenic anti-Dsg3 autoabs bind to different Dsg3 epitopes, leading, among others, to sign...

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Autoren:	Eming, Rüdiger, Riaz, Shafaq, Müller, Eliane J., Zakrzewicz, Anna, Linne, Uwe, Tikkanen, Ritva, Zimmer, Christine Lea, Hudemann, Christoph
Formato:	Artigo
Idioma:	inglês
Publicado em:	Philipps-Universität Marburg 2024
Assuntos:	autoimmunity 2G4 antibody quality control pemphigus vulgaris Medizin PV desmoglein (Dsg) Medical sciences Medicine
Acesso em linha:	Texto integral em PDF
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