AMPK Activation by Cimicifuga racemosa Extract Ze 450 Is Associated with Metabolic Effects and Cellular Resilience against Age-Related Pathologies in Different Tissue Cell Types

AMPK Activation by Cimicifuga racemosa Extract Ze 450 Is Associated with Metabolic Effects and Cellular Resilience against Age-Related Pathologies in Different Tissue Cell Types

Cimicifuga racemosa extracts (CREs) have gained well-established use for the treatment of menopausal symptoms such as hot flushes and excessive sweating, and weight gain. While the clinical effects of CREs have been well documented, the mechanisms underlying these effects are largely unknown. Mor...

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Autoren: Günther, Madeline, Schnierle, Peter, Rose, Thorsten, Schlegel, Jonathan, Boonen, Georg, Drewe, Jürgen, Muñoz, Eduardo, Fiebich, Bernd L., Culmsee, Carsten
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2024
Schlagworte:
3T3L1 adipocytes
herbal extract
HTRF technology
HT22 neuronal cells
Ze 450
Cimicifuga racemosa
AMPK activation
metabolic effects
HEPG2 liver cells
resilience; C2C12 myoblasts
Biowissenschaften, Biologie
Life sciences
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