High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrinecarcinomas from conventional adenocarcinomas with diffuseexpression of synaptophysin

High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrinecarcinomas from conventional adenocarcinomas with diffuseexpression of synaptophysin

Complementary to synaptophysin and chromogranin A, insulinoma-associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms. Since there are no comparative data regarding INSM1 expression in conventional colorectal adenocarcinomas (CRCs) and colorectal...

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Autoren: Litmeyer, Anne-Sophie, Konukiewitz, Björn, Kasajima, Atsuko, Foersch, Sebastian, Schicktanz, Felix, Schmitt, Maxime, Kellers, Franziska, Grass, Albert, Jank, Paul, Lehman, Bettina, Gress, Thomas M., Rinke, Anja, Bartsch, Detlef K., Denkert, Carsten, Weichert, Wilko, Klöppel, Günter, Jesinghaus, Moritz
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
neuroendocrine carcinoma
colorectal carcinoma
conventional adenocarcinoma
INSM1
Medizin
synaptophysin
Medical sciences Medicine
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Signatur: urn:nbn:de:hebis:04-es2024-08185
Publikationsdatum: 2024-02-13
Quelle: Erstveröffentlichung: Litmeyer, A.-S., Konukiewitz, B., Kasajima, A., Foersch, S., Schicktanz, F., Schmitt, M., Kellers, F., Grass, A., Jank, P., Lehman, B., Gress, T.M., Rinke, A., Bartsch, D.K., Denkert, C., Weichert, W., Klöppel, G. and Jesinghaus, M. (2023), High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrine carcinomas from conventional adenocarcinomas with diffuse expression of synaptophysin. J Pathol Clin Res, 9: 498-509. https://doi.org/10.1002/cjp2.339
Downloads: 46 (2024)
Lizenz: https://creativecommons.org/licenses/by-nc-nd/4.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/es/2024/0818
https://doi.org/10.1002/cjp2.339

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