Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis

Korf, Lukas; Ye, Xing; Vogt, Marian S.; Steinchen, Wieland; Watad, Mohamed; van der Does, Chris; Tourte, Maxime; Sivabalasarma, Shamphavi; Albers, Sonja-Verena; Essen, Lars-Oliver

Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis

Three GPN-loop GTPases, GPN1–GPN3, are central to the maturation and trafficking of eukaryotic RNA polymerase II. This GTPase family is widely represented in archaea but typically occurs as single paralogs. Structural analysis of the GTP- and GDP-bound states of the Sulfolobus acidocaldarius GPN enz...

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主要な著者:	Korf, Lukas, Ye, Xing, Vogt, Marian S., Steinchen, Wieland, Watad, Mohamed, van der Does, Chris, Tourte, Maxime, Sivabalasarma, Shamphavi, Albers, Sonja-Verena, Essen, Lars-Oliver,
フォーマット:	論文
言語:	英語
出版事項:	Philipps-Universität Marburg 2023
主題:	RNA polymerase II sulfolobus Chemie GTPase allostery GPN-loop Chemistry & allied sciences
オンライン･アクセス:	PDFフルテキスト
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Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis

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