Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC

Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC

The Shigella pathogenicity factor IpgC belongs to the class II of type III secretion system chaperones, whose members are characterized by a tetratricopeptide repeat (TPR) domain consisting of three and a half TPR motifs. Since IpgC is essential for Shigella virulence, we determined a high-resolu...

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Autoren: Gárdonyi, Marina, Hasewinkel, Christian, Wallbaum, Johanna, Wollenhapt, Jan, Weiss, Manfred S., Klebe, Gerhard, Reuter, Klaus, Heine, Andreas
Formato: Artigo
Idioma:inglés
Publicado: Philipps-Universität Marburg 2023
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Biowissenschaften, Biologie
Life sciences
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