Terahertz Spectroscopy for Non-Destructive Solid-State Investigation of Norfloxacin in Paper Tablets after Wet Granulation

Terahertz Spectroscopy for Non-Destructive Solid-State Investigation of Norfloxacin in Paper Tablets after Wet Granulation

(1) Background: Amorphous drug systems are an intensively studied approach to overcome the insufficient bioavailability of poorly soluble drugs. Here, paper tablets were studied, which were made from cellulose-based paper matrices loaded with norfloxacin. Moreover, wet granulation was introduced...

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Autoren: Heidrich, Lara, Abdelkader, Ayat, Ornik, Jan, Castro-Camus, Enrique, Keck, Cornelia M., Koch, Martin
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
granulation
X-ray powder diffraction; terahertz time-domain spectroscopy
oral drug delivery
solid-state characterization
Biowissenschaften, Biologie
Life sciences
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