Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

Enukashvily, Natella I.; Ponomartsev, Nikita V.; Ketkar, Avanee; Suezov, Roman; Chubar, Anna V.; Prijibelski, Andrey D.; Shafranskaya, Daria D.; Elmshäuser, Sabrina; Keber, Corinna U.; Stefanova, Vera N.; Akopov, Andrey L.; Klingmüller, Ursula; Stiewe, Thorsten; Lauth, Matthias; Brichkina, Anna I.; Pfefferle, Petra I.

Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

The abnormal tumor microenvironment (TME) often dictates the therapeutic response of cancer to chemo- and immuno-therapy. Aberrant expression of pericentromeric satellite repeats has been reported for epithelial cancers, including lung cancer. However, the transcription of tandemly repetitive elemen...

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Autoren:	Enukashvily, Natella I., Ponomartsev, Nikita V., Ketkar, Avanee, Suezov, Roman, Chubar, Anna V., Prijibelski, Andrey D., Shafranskaya, Daria D., Elmshäuser, Sabrina, Keber, Corinna U., Stefanova, Vera N., Akopov, Andrey L., Klingmüller, Ursula, Stiewe, Thorsten, Lauth, Matthias, Brichkina, Anna I., Pfefferle, Petra I.
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2023
Schlagworte:	Cancer microenvironment, Non-small-cell lung cancer Medizin Medical sciences Medicine
Online Zugang:	PDF-Volltext
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Publikationen im Open Access gefördert durch die UB

Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

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