Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

The abnormal tumor microenvironment (TME) often dictates the therapeutic response of cancer to chemo- and immuno-therapy. Aberrant expression of pericentromeric satellite repeats has been reported for epithelial cancers, including lung cancer. However, the transcription of tandemly repetitive elemen...

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Autori principali: Enukashvily, Natella I., Ponomartsev, Nikita V., Ketkar, Avanee, Suezov, Roman, Chubar, Anna V., Prijibelski, Andrey D., Shafranskaya, Daria D., Elmshäuser, Sabrina, Keber, Corinna U., Stefanova, Vera N., Akopov, Andrey L., Klingmüller, Ursula, Stiewe, Thorsten, Lauth, Matthias, Brichkina, Anna I., Pfefferle, Petra I.
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2023
Soggetti:
Cancer microenvironment, Non-small-cell lung cancer
Medizin
Medical sciences Medicine
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