Generation of a Syngeneic Heterozygous ACVRL1(wt/mut) Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis
Hereditary hemorrhagic telangiectasia (HHT) type 2 is an autosomal dominant disease in which one allele of the ACVRL1 gene is mutated. Patients exhibit disturbances in TGF-beta/BMP-dependent angiogenesis and, clinically, often present with severe nosebleeds as well as a reduced quality of life. The...
Sábháilte in:
Príomhchruthaitheoirí: | , , , , , , , , , , |
---|---|
Formáid: | Alt |
Teanga: | Béarla |
Foilsithe / Cruthaithe: |
Philipps-Universität Marburg
2023
|
Ábhair: | |
Rochtain ar líne: | An téacs iomlán mar PDF |
Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|
Publikationen im Open Access gefördert durch die UB