Co-Delivery of Ylang Ylang Oil of Cananga odorata and Oxaliplatin Using Intelligent pH-Sensitive Lipid-Based Nanovesicles for the Effective Treatment of Triple-Negative Breast Cancer

Co-Delivery of Ylang Ylang Oil of Cananga odorata and Oxaliplatin Using Intelligent pH-Sensitive Lipid-Based Nanovesicles for the Effective Treatment of Triple-Negative Breast Cancer

Smart pH-responsive niosomes loaded with either Oxaliplatin (Ox), Ylang ylang essential oil (Y-oil), or co-loaded with both compounds (Ox-Y) (Ox@NSs, Y@NSs, and Ox-Y@NSs, respectively) were formulated utilizing the thin film method. The developed nanocontainers had a spherical morphology with mea...

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Autoren: Sedky, Nada K., Abdel-Kader, Nour M., Issa, Marwa Y., Abdelhady, Manal M. M., Shamma, Samir N., Bakowsky, Udo, Fahmy, Sherif Ashraf
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
essential oils
oxaliplatin
niosomes
apoptosis
cytotoxicity; invasive breast cancer
platinum-based anticancer drugs
Biowissenschaften, Biologie
intrinsic pathway
Life sciences
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