Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase
Background: In vivo gene editing of somatic cells with CRISPR nucleases has facilitated the generation of autochthonous mouse tumors, which are initiated by genetic alterations relevant to the human disease and progress along a natural timeline as in patients. However, the long and variable, ortho...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , |
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Format: | Article |
Langue: | anglais |
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Philipps-Universität Marburg
2022
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