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Rhabdomyolysis in children in acute and chronic disease - a challenging condition in pediatric emergency medicine

Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), a...

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Bibliographic Details
Main Authors: Mand, Nadine, Donath, Carolin, Leonhardt, A., Weber, S., Kömhoff, Martin
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
rhabdomyolysis
Medizin
circulatory failure
LPIN1 mutation
hereditary metabolic disease
acute kidney injury (AKI)
Medical sciences Medicine
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Summary:Rhabdomyolysis is a challenging condition in pediatric emergency departments (PED): It ranges from asymptomatic illness with isolated elevation of creatine kinase (CK) levels to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, circulatory failure (CF), acute kidney injury (AKI), and multi-organ disease. Most common causes of rhabdomyolysis are viral myositis and trauma, hereditary metabolic myopathies must be considered when facing rhabdomyolysis in early childhood. We report two cases of severe rhabdomyolysis with CF in our PED, thereby summarizing first-line management of rhabdomyolysis.
Item Description:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
DOI:10.3389/fped.2023.1070465

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