IL18 Receptor Signaling Inhibits Intratumoral CD8+ T-Cell Migration in a Murine Pancreatic Cancer Model

IL18 Receptor Signaling Inhibits Intratumoral CD8+ T-Cell Migration in a Murine Pancreatic Cancer Model

In pancreatic ductal adenocarcinoma (PDAC), the infiltration of CD8+ cytotoxic T cells (CTLs) is an important factor in determining prognosis. The migration pattern and interaction behavior of intratumoral CTLs are pivotal to tumor rejection. NLRP3-dependent proinflammatory cytokines IL-1β and IL-18...

詳細記述

保存先:
書誌詳細
主要な著者: Nasiri, Elena, Student, Malte, Roth, Katrin, Siti Utami, Nadya, Huber, Magdalena, Buchholz, Malte, Gress, Thomas M., Bauer, Christian
フォーマット: 論文
言語:英語
出版事項: Philipps-Universität Marburg 2023
主題:
cytokines
live cell imaging
pausing phases/arrest coefficient
Medizin
fluorophore
T-cell plasticity
intravital two-photon microscopy animal models for intravital imaging
pancreatic carcinoma
tumor spheroid coculture model
T-cell migration
Medical sciences Medicine
オンライン･アクセス:PDFフルテキスト
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
Publikationen im Open Access gefördert durch die UB

類似資料