The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin regulators, facilitating histone acetylation. Dysregulation of KAT6A has been implicated in developmental syndromes and the onset of acute myeloid leukemia (AML). Previous work suggests that KAT6A is recruited to...

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Manylion Llyfryddiaeth
Prif Awduron: Weber, Lisa Marie, Jia, Yulin, Stielow, Bastian, Gisselbrecht, Stephen S., Cao, Yinghua, Ren, Yanpeng, Rohner, Iris, King, Jessica, Rothman, Elisabeth, Fischer, Sabrina, Simon, Clara, Forné, Ignasi, Nist, Andrea, Stiewe, Thorsten, Bulyk, Martha L., Wang, Zhanxin, Liefke, Robert
Fformat: Erthygl
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2023
Pynciau:
Medizin
Medical sciences Medicine
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Rhif Galw: urn:nbn:de:hebis:04-es2024-02287
Dyddiad Cyhoeddi: 2024-01-09
Ffynhonnell: Erstveröffentlichung: Weber LM, Jia Y, Stielow B, Gisselbrecht SS, Cao Y, Ren Y, Rohner I, King J, Rothman E, Fischer S, Simon C, Forné I, Nist A, Stiewe T, Bulyk ML, Wang Z, Liefke R. The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain. Nucleic Acids Res. 2023 Jan 25;51(2):574-594. doi: 10.1093/nar/gkac1188
Downloads: 20 (2024)
Lizenz: https://creativecommons.org/licenses/by/4.0
URL mynediad: https://archiv.ub.uni-marburg.de/es/2024/0228
https://doi.org/10.1093/nar/gkac1188

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